Varaico: Literature-Extracted Genetic Variants

NCOA3

384 papers

RefSeq Summary

The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone a...

Pfam Domains

bHLH_NCOAaa 1–79UCSCNuclear receptor coactivators bHLH domain

PASaa 113–211UCSCPAS fold

PAS_11aa 264–375UCSCPAS domain

NCOA_u2aa 459–572UCSCUnstructured region on nuclear receptor coactivator protein

SRC-1aa 616–704UCSCSteroid receptor coactivator

DUF4927aa 723–810UCSCDomain of unknown function (DUF4927)

Gene Aliases

HGNC Name

nuclear receptor coactivator 3

HGNC Alias Symbols

AIB1; p/CIP; TRAM-1; CAGH16; TNRC16; KAT13B; bHLHe42; SRC-3; SRC3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_181659.3

p.F1238_Q1241del0

c.3714_3722del9

Surrounding Variants

1 paper

NM_181659.3

p.R1239*

c.3715C>T

1 paper

NM_181659.3

p.V1243_M1246del4

c.3727_3737del12

1 paper

NM_181659.3

p.V1243_A1244del2

c.3727_3731del6

1 paper

NM_181659.3

p.E1232V

c.3695A>T

1 paper

NM_181659.3

p.E1232*

c.3694G>T

6 papers

NM_181659.3

p.M1246del1

c.3736_3738delATG

2 papers

NM_181659.3

p.M1246_M1247del0

c.3736_3741del6

6 papers

NM_181659.3

p.M1246_Q1249del4

c.3736_3746del12

6 papers

NM_181659.3

p.M1247_Q1249del3

c.3739_3746del9

1 paper

NM_181659.3

p.M1246_Q1249delFs

c.3738_3747del10

1 paper

NM_181659.3

p.M1247_Q1250del4

c.3739_3749del12

1 paper

NM_181659.3

p.R1229H

c.3686G>A