Varaico: Literature-Extracted Genetic Variants

NCOA3

384 papers

RefSeq Summary

The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone a...

Pfam Domains

bHLH_NCOAaa 1–79UCSCNuclear receptor coactivators bHLH domain

PASaa 113–211UCSCPAS fold

PAS_11aa 264–375UCSCPAS domain

NCOA_u2aa 459–572UCSCUnstructured region on nuclear receptor coactivator protein

SRC-1aa 616–704UCSCSteroid receptor coactivator

DUF4927aa 723–810UCSCDomain of unknown function (DUF4927)

Gene Aliases

HGNC Name

nuclear receptor coactivator 3

HGNC Alias Symbols

AIB1; p/CIP; TRAM-1; CAGH16; TNRC16; KAT13B; bHLHe42; SRC-3; SRC3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001174087.2

p.Q1255_Q1256insFs

c.3765_3766insG

Surrounding Variants

1 paper

NM_001174087.2

p.Q1255insFs

c.3764_3765insGC

1 paper

NM_181659.3

p.Q1259ins4

c.3776_3777ins12

1 paper

NM_181659.3

p.Q1258ins1

c.3773_3774insACA

2 papers

NM_181659.3

p.Q1262_Q1264ins1

c.3786_3791dup6

1 paper

NM_181659.3

p.Q1254Q

c.3762A>G

8 papers

NM_181659.3

p.Q1263_Q1264del1

c.3789_3791delGCA

2 papers

NM_181659.3

p.Q1262_Q1264del0

c.3786_3791del6

1 paper

NM_181659.3

p.Q1259_Q1264del0

c.3777_3791del15

1 paper

NM_181659.3

p.Q1253Q

c.3759G>A

5 papers

NM_181659.3

p.Q1254del1

c.3760_3761delCAA

1 paper

NM_181659.3

p.Q1253_Q1256delins

c.3759_3768delinsA

1 paper

NM_181659.3

p.Q1259insFs

c.3776_3777ins10