Varaico: Literature-Extracted Genetic Variants

NCOA3

384 papers

RefSeq Summary

The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone a...

Pfam Domains

bHLH_NCOAaa 1–79UCSCNuclear receptor coactivators bHLH domain

PASaa 113–211UCSCPAS fold

PAS_11aa 264–375UCSCPAS domain

NCOA_u2aa 459–572UCSCUnstructured region on nuclear receptor coactivator protein

SRC-1aa 616–704UCSCSteroid receptor coactivator

DUF4927aa 723–810UCSCDomain of unknown function (DUF4927)

Gene Aliases

HGNC Name

nuclear receptor coactivator 3

HGNC Alias Symbols

AIB1; p/CIP; TRAM-1; CAGH16; TNRC16; KAT13B; bHLHe42; SRC-3; SRC3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_181659.3

p.P1306L

c.3917C>T

Surrounding Variants

1 paper

NM_181659.3

p.A1304T

c.3910G>A

1 paper

NM_181659.3

p.Y1311F

c.3932A>T

1 paper

NM_181659.3

p.Y1315C

c.3944A>G

1 paper

NM_181659.3

p.M1292I

c.3876G>A

1 paper

NM_181659.3

p.M1292I

c.3876G>C

1 paper

NM_181659.3

p.M1292I

c.3876G>T

1 paper

NM_181659.3

p.M1292T

c.3875T>C

1 paper

NM_181659.3

p.P1282S

c.3844C>T

7 papers

NM_181659.3

p.Q1276del1

c.3826_3827delCAA

1 paper

NM_181659.3

p.Q1275_Q1276del2

c.3823_3827del6

4 papers

NM_181659.3

p.Q1275del1

c.3823_3824delCAG

1 paper

NM_181659.3

p.Q1273_Q1275delFs

c.3819_3823del5