Varaico: Literature-Extracted Genetic Variants

NCOR1

708 papers

RefSeq Summary

This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the tr...

Pfam Domains

GPS2_interactaa 149–238UCSCG-protein pathway suppressor 2-interacting domain

Myb_DNA-bindingaa 625–670UCSCMyb-like DNA-binding domain

NCOR1_Naa 1915–1944UCSCNuclear receptor corepressor 1 N-terminal domain

Gene Aliases

HGNC Name

nuclear receptor corepressor 1

HGNC Alias Symbols

N-CoR; hCIT529I10; TRAC1; hN-CoR; KIAA1047; MGC104216; PPP1R109

Papers

RefSeq ID

Protein change

DNA change

1–12 of 1133 variants

19 papers

NM_006311.4

p.S172L

c.515C>T

18 papers

NM_006311.4

p.K178N

c.534G>T

18 papers

NM_006311.4

p.K178N

c.534G>C

16 papers

NM_006311.4

p.G5V

c.14G>T

16 papers

NM_006311.4

p.G150R

c.448G>C

16 papers

NM_006311.4

p.G150R

c.448G>A

14 papers

NM_006311.4

p.R190*

c.568C>T

11 papers

NM_006311.4

p.Y20S

c.59A>C

11 papers

NM_006311.4

p.Q26K

c.76C>A

11 papers

NM_006311.4

p.A2182T

c.6544G>A

9 papers

NM_006311.4

p.E191K

c.571G>A

9 papers

NM_006311.4

p.H2252Y

c.6754C>T