Varaico: Literature-Extracted Genetic Variants

NCOR1

708 papers

RefSeq Summary

This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the tr...

Pfam Domains

GPS2_interactaa 149–238UCSCG-protein pathway suppressor 2-interacting domain

Myb_DNA-bindingaa 625–670UCSCMyb-like DNA-binding domain

NCOR1_Naa 1915–1944UCSCNuclear receptor corepressor 1 N-terminal domain

Gene Aliases

HGNC Name

nuclear receptor corepressor 1

HGNC Alias Symbols

N-CoR; hCIT529I10; TRAC1; hN-CoR; KIAA1047; MGC104216; PPP1R109

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006311.4

p.I2188V

c.6562A>G

Surrounding Variants

1 paper

NM_006311.4

p.S2184*

c.6551C>G

1 paper

NM_006311.4

p.S2184*

c.6551C>A

1 paper

NM_006311.4

p.R2183L

c.6548G>T

3 papers

NM_006311.4

p.R2183H

c.6548G>A

1 paper

NM_006311.4

p.S2193*

c.6578C>G

1 paper

NM_006311.4

p.S2193*

c.6578C>A

1 paper

NM_006311.4

p.S2193S

c.6579A>C

11 papers

NM_006311.4

p.A2182T

c.6544G>A

3 papers

NM_006311.4

p.R2179T

c.6536G>C

1 paper

NM_006311.4

p.K2197N

c.6591G>T

1 paper

NM_006311.4

p.K2197N

c.6591G>C

1 paper

NM_006311.4

p.S2202*

c.6605C>G