Varaico: Literature-Extracted Genetic Variants

NCOR1

708 papers

RefSeq Summary

This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the tr...

Pfam Domains

GPS2_interactaa 149–238UCSCG-protein pathway suppressor 2-interacting domain

Myb_DNA-bindingaa 625–670UCSCMyb-like DNA-binding domain

NCOR1_Naa 1915–1944UCSCNuclear receptor corepressor 1 N-terminal domain

Gene Aliases

HGNC Name

nuclear receptor corepressor 1

HGNC Alias Symbols

N-CoR; hCIT529I10; TRAC1; hN-CoR; KIAA1047; MGC104216; PPP1R109

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006311.4

p.D189_R190delFs

c.566_569del4

Surrounding Variants

1 paper

NM_006311.4

p.E191insFs

c.571_572insC

9 papers

NM_006311.4

p.E191K

c.571G>A

1 paper

NM_006311.4

p.R190_E191delins

c.568_571delinsTGAA

3 papers

NM_006311.4

p.R190L

c.569G>T

1 paper

NM_006311.4

p.R190P

c.569G>C

14 papers

NM_006311.4

p.R190*

c.568C>T

1 paper

NM_006311.4

p.I192N

c.575T>A

1 paper

NM_006311.4

p.D189V

c.566A>T

1 paper

NM_006311.4

p.A193P

c.577G>C

2 papers

NM_006311.4

p.D189N

c.565G>A

1 paper

NM_006311.4

p.A193fs

c.577_578fs

1 paper

NM_006311.4

p.V188_D189insFs

c.564_565insGC