Varaico: Literature-Extracted Genetic Variants

NCOR1

708 papers

RefSeq Summary

This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the tr...

Pfam Domains

GPS2_interactaa 149–238UCSCG-protein pathway suppressor 2-interacting domain

Myb_DNA-bindingaa 625–670UCSCMyb-like DNA-binding domain

NCOR1_Naa 1915–1944UCSCNuclear receptor corepressor 1 N-terminal domain

Gene Aliases

HGNC Name

nuclear receptor corepressor 1

HGNC Alias Symbols

N-CoR; hCIT529I10; TRAC1; hN-CoR; KIAA1047; MGC104216; PPP1R109

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006311.4

p.E180D

c.540G>T

Surrounding Variants

3 papers

NM_006311.4

p.E180D

c.540G>C

1 paper

NM_006311.4

p.E180*

c.538G>T

18 papers

NM_006311.4

p.K178N

c.534G>T

18 papers

NM_006311.4

p.K178N

c.534G>C

1 paper

NM_006311.4

p.L176_K178delins

c.528_534delinsTTCAAAC

2 papers

NM_006311.4

p.Q183E

c.547C>G

1 paper

NM_006311.4

p.S174_K178Fs

c.522_534delinsGGFs

2 papers

NM_006311.4

p.S184C

c.550A>T

3 papers

NM_006311.4

p.L176L

c.528C>T

1 paper

NM_006311.4

p.S174*

c.521C>G

1 paper

NM_006311.4

p.S174*

c.521C>A

1 paper

NM_006311.4

p.R187L

c.560G>T