Varaico: Literature-Extracted Genetic Variants

NCOR1

708 papers

RefSeq Summary

This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the tr...

Pfam Domains

GPS2_interactaa 149–238UCSCG-protein pathway suppressor 2-interacting domain

Myb_DNA-bindingaa 625–670UCSCMyb-like DNA-binding domain

NCOR1_Naa 1915–1944UCSCNuclear receptor corepressor 1 N-terminal domain

Gene Aliases

HGNC Name

nuclear receptor corepressor 1

HGNC Alias Symbols

N-CoR; hCIT529I10; TRAC1; hN-CoR; KIAA1047; MGC104216; PPP1R109

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006311.4

p.P159T

c.475C>A

Surrounding Variants

1 paper

NM_006311.4

p.S161L

c.482C>T

1 paper

NM_006311.4

p.P156P

c.468A>G

1 paper

NM_006311.4

p.P156Q

c.467C>A

1 paper

NM_006311.4

p.G162R

c.484G>C

1 paper

NM_006311.4

p.G162R

c.484G>A

1 paper

NM_006311.4

p.A155V

c.464C>T

1 paper

NM_006311.4

p.H153R

c.458A>G

1 paper

NM_006311.4

p.P147_H153insFs

c.439_457dup19

1 paper

NM_006311.4

p.G151S

c.451G>A

1 paper

NM_006311.4

p.D167fs

c.499_500fs

16 papers

NM_006311.4

p.G150R

c.448G>C

16 papers

NM_006311.4

p.G150R

c.448G>A