Varaico: Literature-Extracted Genetic Variants

NCOR1

708 papers

RefSeq Summary

This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the tr...

Pfam Domains

GPS2_interactaa 149–238UCSCG-protein pathway suppressor 2-interacting domain

Myb_DNA-bindingaa 625–670UCSCMyb-like DNA-binding domain

NCOR1_Naa 1915–1944UCSCNuclear receptor corepressor 1 N-terminal domain

Gene Aliases

HGNC Name

nuclear receptor corepressor 1

HGNC Alias Symbols

N-CoR; hCIT529I10; TRAC1; hN-CoR; KIAA1047; MGC104216; PPP1R109

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_006311.4

p.N31S

c.92A>G

Surrounding Variants

2 papers

NM_006311.4

p.R33C

c.97C>T

2 papers

NM_006311.4

p.R33H

c.98G>A

2 papers

NM_006311.4

p.T28T

c.84A>G

1 paper

NM_006311.4

p.H34Q

c.102C>G

1 paper

NM_006311.4

p.H34Q

c.102C>A

1 paper

NM_006311.4

p.T28P

c.82A>C

1 paper

NM_006311.4

p.Y27delFs

c.80delT

1 paper

NM_006311.4

p.Q35fs

c.103_104fs

1 paper

NM_006311.4

p.Q35L

c.104A>T

1 paper

NM_006311.4

p.Y27N

c.79T>A

1 paper

NM_006311.4

p.Q35H

c.105G>T

1 paper

NM_006311.4

p.Q35H

c.105G>C