Varaico: Literature-Extracted Genetic Variants

NCOR1

708 papers

RefSeq Summary

This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the tr...

Pfam Domains

GPS2_interactaa 149–238UCSCG-protein pathway suppressor 2-interacting domain

Myb_DNA-bindingaa 625–670UCSCMyb-like DNA-binding domain

NCOR1_Naa 1915–1944UCSCNuclear receptor corepressor 1 N-terminal domain

Gene Aliases

HGNC Name

nuclear receptor corepressor 1

HGNC Alias Symbols

N-CoR; hCIT529I10; TRAC1; hN-CoR; KIAA1047; MGC104216; PPP1R109

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006311.4

p.R19C

c.55C>T

Surrounding Variants

1 paper

NM_006311.4

p.R19P

c.56G>C

4 papers

NM_006311.4

p.R19H

c.56G>A

1 paper

NM_006311.4

p.Y20N

c.58T>A

2 papers

NM_006311.4

p.Y20F

c.59A>T

11 papers

NM_006311.4

p.Y20S

c.59A>C

1 paper

NM_006311.4

p.P21S

c.61C>T

1 paper

NM_006311.4

p.E16D

c.48A>T

1 paper

NM_006311.4

p.E16V

c.47A>T

1 paper

NM_006311.4

p.E16K

c.46G>A

2 papers

NM_006311.4

p.P22L

c.65C>T

1 paper

NM_006311.4

p.F13V

c.37T>G

3 papers

NM_006311.4

p.V25V

c.75C>A