Varaico: Literature-Extracted Genetic Variants

NCOR2

573 papers

RefSeq Summary

This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid rec...

Pfam Domains

GPS2_interactaa 141–229UCSCG-protein pathway suppressor 2-interacting domain

Myb_DNA-bindingaa 428–473UCSCMyb-like DNA-binding domain

Myb_DNA-bindingaa 611–656UCSCMyb-like DNA-binding domain

Gene Aliases

HGNC Name

nuclear receptor corepressor 2

HGNC Alias Symbols

SMRT; SMRTE; TRAC-1; CTG26; TNRC14

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

6 papers

NM_006312.6

p.S647L

c.1940C>T

Surrounding Variants

1 paper

NM_006312.6

p.M640V

c.1918A>G

1 paper

NM_006312.6

p.Y656*

c.1968C>G

1 paper

NM_006312.6

p.Y656*

c.1968C>A

1 paper

NM_006312.6

p.S635L

c.1904C>T

1 paper

NM_006312.6

p.H630Y

c.1888C>T

1 paper

NM_006312.6

p.L627_L628insFs

c.1881_1882insC

1 paper

NM_006312.6

p.L666F

c.1998G>T

1 paper

NM_006312.6

p.L666F

c.1998G>C

2 papers

NM_006312.6

p.Q667L

c.2000A>T

1 paper

NM_006312.6

p.Q668L

c.2003A>T

1 paper

NM_006312.6

p.K675del1

c.2023_2024delCTT

2 papers

NM_006312.6

p.N678T

c.2033A>C