Varaico: Literature-Extracted Genetic Variants

NDC80

114 papers

RefSeq Summary

This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other...

Pfam Domains

Ndc80_HECaa 51–198UCSCHEC/Ndc80p family

DUF5595aa 213–285UCSCDomain of unknown function (DUF5595)

NDC80_loopaa 377–609UCSCKinetochore protein NDC80 loop region

Gene Aliases

HGNC Name

NDC80 kinetochore complex component

HGNC Previous Symbol

KNTC2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006101.3

p.D157N

c.469G>A

Surrounding Variants

1 paper

NM_006101.3

p.L158F

c.472C>T

1 paper

NM_006101.3

p.F155F

c.465T>C

1 paper

NM_006101.3

p.E150A

c.449A>C

1 paper

NM_006101.3

p.T145A

c.433A>G

1 paper

NM_006101.3

p.V122L

c.364G>C

1 paper

NM_006101.3

p.K115E

c.343A>G

1 paper

NM_006101.3

p.S113F

c.338C>T

1 paper

NM_006101.3

p.L103L

c.309T>A

1 paper

NM_006101.3

p.F102S

c.305T>C

1 paper

NM_006101.3

p.R97Q

c.290G>A

1 paper

NM_006101.3

p.I96V

c.286A>G

1 paper

NM_006101.3

p.D88N

c.262G>A