Varaico: Literature-Extracted Genetic Variants

NECTIN1

178 papers

RefSeq Summary

This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell...

Pfam Domains

V-setaa 34–143UCSCImmunoglobulin V-set domain

C2-set_2aa 148–237UCSCCD80-like C2-set immunoglobulin domain

Ig_3aa 246–320UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

nectin cell adhesion molecule 1

HGNC Previous Symbols

HVEC; ED4; PVRL1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002855.5

p.I369V

c.1105A>G

Surrounding Variants

1 paper

NM_002855.5

p.V370L

c.1108G>C

1 paper

NM_002855.5

p.V367M

c.1099G>A

1 paper

NM_002855.5

p.V360M

c.1078G>A

1 paper

NM_002855.5

p.R380Q

c.1139G>A

2 papers

NM_002855.5

p.I357T

c.1070T>C

1 paper

NM_002855.5

p.R381C

c.1141C>T

1 paper

NM_002855.5

p.R382Q

c.1145G>A

1 paper

NM_002855.5

p.P351_T354del0

c.1052_1060del9

1 paper

NM_002855.5

p.A355T

c.1063G>A

1 paper

NM_002855.5

p.P351L

c.1052C>T

1 paper

NM_002855.5

p.G350W

c.1048G>T

1 paper

NM_002855.5

p.A349A

c.1047C>T