Varaico: Literature-Extracted Genetic Variants

Gene:NEIL2
Variant:p.R257L

NEIL2

98 papers

RefSeq Summary

This gene encodes a member of the Fpg/Nei family of DNA glycosylases. These glycosylases initiate the first step in base excision repair by cleaving oxidatively damaged bases and introducing a DNA str...

Pfam Domains

H2THaa 193–275UCSCFormamidopyrimidine-DNA glycosylase H2TH domain

Gene Aliases

HGNC Name

nei like DNA glycosylase 2

HGNC Alias Symbols

NEH2; FLJ31644; MGC2832; MGC4505

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
12 papers
NM_145043.4
p.R257L
c.770G>T
Surrounding Variants
1 paper
NM_145043.4
p.R257W
c.769C>T
2 papers
NM_145043.4
p.R256C
c.766C>T
3 papers
NM_145043.4
p.V264M
c.790G>A
1 paper
NM_145043.4
p.G249D
c.746G>A
2 papers
NM_145043.4
p.G249S
c.745G>A
1 paper
NM_145043.4
p.E266D
c.798G>C
1 paper
NM_145043.4
p.P245S
c.733C>T
1 paper
NM_145043.4
p.H244R
c.731A>G
1 paper
NM_145043.4
p.G242W
c.724G>T
1 paper
NM_145043.4
p.K234delFs
c.702delG
1 paper
NM_145043.4
p.K234fs
c.700_701fs
1 paper
NM_145043.4
p.Q281fs
c.841_842fs
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."