Varaico: Literature-Extracted Genetic Variants

NEIL3

91 papers

RefSeq Summary

NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen...

Pfam Domains

H2THaa 153–231UCSCFormamidopyrimidine-DNA glycosylase H2TH domain

Zn_ribbon_RanBPaa 317–346UCSCZn-finger in Ran binding protein and others

Zn_ribbon_GRFaa 505–550UCSCGRF zinc finger

Zn_ribbon_GRFaa 552–596UCSCGRF zinc finger

Gene Aliases

HGNC Name

nei like DNA glycosylase 3

HGNC Alias Symbols

FLJ10858; hFPG2; FPG2; hNEI3; ZGRF3

Papers

RefSeq ID

Protein change

DNA change

1–12 of 114 variants

8 papers

NM_018248.3

p.D132V

c.395A>T

7 papers

NM_018248.3

p.A547S

c.1639G>T

6 papers

NM_018248.3

p.P117R

c.350C>G

6 papers

NM_018248.3

p.Q172H

c.516G>C

6 papers

NM_018248.3

p.Q172H

c.516G>T

6 papers

NM_018248.3

p.A241S

c.721G>T

5 papers

NM_018248.3

p.Q471H

c.1413A>C

5 papers

NM_018248.3

p.Q471H

c.1413A>T

4 papers

NM_018248.3

p.R559H

c.1676G>A

3 papers

NM_018248.3

p.L199V

c.595C>G

3 papers

NM_018248.3

p.H286R

c.857A>G

3 papers

NM_018248.3

p.I346V

c.1036A>G