Varaico: Literature-Extracted Genetic Variants

NEIL3

91 papers

RefSeq Summary

NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen...

Pfam Domains

H2THaa 153–231UCSCFormamidopyrimidine-DNA glycosylase H2TH domain

Zn_ribbon_RanBPaa 317–346UCSCZn-finger in Ran binding protein and others

Zn_ribbon_GRFaa 505–550UCSCGRF zinc finger

Zn_ribbon_GRFaa 552–596UCSCGRF zinc finger

Gene Aliases

HGNC Name

nei like DNA glycosylase 3

HGNC Alias Symbols

FLJ10858; hFPG2; FPG2; hNEI3; ZGRF3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

6 papers

NM_018248.3

p.Q172H

c.516G>C

Surrounding Variants

6 papers

NM_018248.3

p.Q172H

c.516G>T

1 paper

NM_018248.3

p.R175G

c.523C>G

1 paper

NM_018248.3

p.R175W

c.523C>T

1 paper

NM_018248.3

p.D179N

c.535G>A

1 paper

NM_018248.3

p.V186I

c.556G>A

1 paper

NM_018248.3

p.S157fs

c.469_470fs

1 paper

NM_018248.3

p.I193V

c.577A>G

1 paper

NM_018248.3

p.I193Fs

c.578delinsTAFs

1 paper

NM_018248.3

p.M149T

c.446T>C

3 papers

NM_018248.3

p.L199V

c.595C>G

1 paper

NM_018248.3

p.L199F

c.595C>T

2 papers

NM_018248.3

p.Q144P

c.431A>C