Varaico: Literature-Extracted Genetic Variants

NEIL3

91 papers

RefSeq Summary

NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen...

Pfam Domains

H2THaa 153–231UCSCFormamidopyrimidine-DNA glycosylase H2TH domain

Zn_ribbon_RanBPaa 317–346UCSCZn-finger in Ran binding protein and others

Zn_ribbon_GRFaa 505–550UCSCGRF zinc finger

Zn_ribbon_GRFaa 552–596UCSCGRF zinc finger

Gene Aliases

HGNC Name

nei like DNA glycosylase 3

HGNC Alias Symbols

FLJ10858; hFPG2; FPG2; hNEI3; ZGRF3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_018248.3

p.P277S

c.829C>T

Surrounding Variants

1 paper

NM_018248.3

p.C276F

c.827G>T

1 paper

NM_018248.3

p.R271fs

c.811_812fs

1 paper

NM_018248.3

p.R271_M272delFs

c.812_815del4

3 papers

NM_018248.3

p.H286R

c.857A>G

2 papers

NM_018248.3

p.R265H

c.794G>A

1 paper

NM_018248.3

p.C290Y

c.869G>A

1 paper

NM_018248.3

p.T262T

c.786T>A

1 paper

NM_018248.3

p.G255fs

c.763_764fs

1 paper

NM_018248.3

p.P252P

c.756T>C

1 paper

NM_018248.3

p.R251H

c.752G>A

1 paper

NM_018248.3

p.H245Y

c.733C>T

6 papers

NM_018248.3

p.A241S

c.721G>T