Varaico: Literature-Extracted Genetic Variants

NEIL3

91 papers

RefSeq Summary

NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen...

Pfam Domains

H2THaa 153–231UCSCFormamidopyrimidine-DNA glycosylase H2TH domain

Zn_ribbon_RanBPaa 317–346UCSCZn-finger in Ran binding protein and others

Zn_ribbon_GRFaa 505–550UCSCGRF zinc finger

Zn_ribbon_GRFaa 552–596UCSCGRF zinc finger

Gene Aliases

HGNC Name

nei like DNA glycosylase 3

HGNC Alias Symbols

FLJ10858; hFPG2; FPG2; hNEI3; ZGRF3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_018248.3

p.V424V

c.1272T>G

Surrounding Variants

1 paper

NM_018248.3

p.K435Q

c.1303A>C

1 paper

NM_018248.3

p.E414K

c.1240G>A

1 paper

NM_018248.3

p.L412L

c.1234C>T

1 paper

NM_018248.3

p.T406I

c.1217C>T

3 papers

NM_018248.3

p.P443L

c.1328C>T

1 paper

NM_018248.3

p.E403delFs

c.1209delA

1 paper

NM_018248.3

p.N397S

c.1190A>G

1 paper

NM_018248.3

p.T389I

c.1166C>T

1 paper

NM_018248.3

p.F460C

c.1379T>G

1 paper

NM_018248.3

p.P462T

c.1384C>A

1 paper

NM_018248.3

p.K466insFs

c.1398dupA

1 paper

NM_018248.3

p.K466T

c.1397A>C