Varaico: Literature-Extracted Genetic Variants

NEIL3

91 papers

RefSeq Summary

NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen...

Pfam Domains

H2THaa 153–231UCSCFormamidopyrimidine-DNA glycosylase H2TH domain

Zn_ribbon_RanBPaa 317–346UCSCZn-finger in Ran binding protein and others

Zn_ribbon_GRFaa 505–550UCSCGRF zinc finger

Zn_ribbon_GRFaa 552–596UCSCGRF zinc finger

Gene Aliases

HGNC Name

nei like DNA glycosylase 3

HGNC Alias Symbols

FLJ10858; hFPG2; FPG2; hNEI3; ZGRF3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

7 papers

NM_018248.3

p.A547S

c.1639G>T

Surrounding Variants

1 paper

NM_018248.3

p.L549F

c.1647G>T

1 paper

NM_018248.3

p.F553S

c.1658T>C

2 papers

NM_018248.3

p.H556R

c.1667A>G

1 paper

NM_018248.3

p.R559C

c.1675C>T

4 papers

NM_018248.3

p.R559H

c.1676G>A

3 papers

NM_018248.3

p.M562T

c.1685T>C

1 paper

NM_018248.3

p.K567E

c.1699A>G

1 paper

NM_018248.3

p.E545_W546Splc

c.1636-73A>G

1 paper

NM_018248.3

p.N572S

c.1715A>G

1 paper

NM_018248.3

p.N575fs

c.1723_1724fs

1 paper

NM_018248.3

p.F577insFs

c.1731dupT

1 paper

NM_018248.3

p.V578fs

c.1732_1733fs