Varaico: Literature-Extracted Genetic Variants

Gene:NEXN
Variant:p.R391*

NEXN

267 papers

RefSeq Summary

This gene encodes a filamentous actin-binding protein that may function in cell adhesion and migration. Mutations in this gene have been associated with dilated cardiomyopathy, also known as CMD1CC. A...

Pfam Domains

I-setaa 582–671UCSCImmunoglobulin I-set domain

Gene Aliases

HGNC Name

nexilin F-actin binding protein

HGNC Alias Symbols

nexilin; NELIN

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
5 papers
NM_144573.4
p.R391*
c.1171C>T
Surrounding Variants
2 papers
NM_144573.4
p.R391Q
c.1172G>A
1 paper
NM_144573.4
p.K390E
c.1168A>G
16 papers
NM_144573.4
p.R392*
c.1174C>T
1 paper
NM_144573.4
p.R392Q
c.1175G>A
1 paper
NM_144573.4
p.T393K
c.1178C>A
1 paper
NM_144573.4
p.E388*
c.1162G>T
4 papers
NM_144573.4
p.M386fs
c.1156_1157fs
1 paper
NM_144573.4
p.M386fs
c.1156_1157fs
1 paper
NM_144573.4
p.R397W
c.1189C>T
3 papers
NM_144573.4
p.R397Q
c.1190G>A
5 papers
NM_144573.4
p.M386insFs
c.1156dupA
1 paper
NM_144573.4
p.Q384fs
c.1150_1151fs
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