Varaico: Literature-Extracted Genetic Variants

NFKB2

572 papers

RefSeq Summary

This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involv...

Pfam Domains

RHD_DNA_bindaa 40–220UCSCRel homology DNA-binding domain

RHD_dimeraa 229–329UCSCRel homology dimerisation domain

Ankaa 487–521UCSCAnkyrin repeat

Ankaa 526–558UCSCAnkyrin repeat

Ankaa 599–631UCSCAnkyrin repeat

Ankaa 633–666UCSCAnkyrin repeat

Gene Aliases

HGNC Name

nuclear factor kappa B subunit 2

HGNC Alias Symbols

LYT-10; p52; p105; NF-kB2; p49/p100

Papers

RefSeq ID

Protein change

DNA change

1–12 of 504 variants

37 papers

NM_001322934.2

p.R853*

c.2557C>T

20 papers

NM_001322934.2

p.D865G

c.2594A>G

19 papers

NM_001322934.2

p.A867V

c.2600C>T

13 papers

NM_001322934.2

p.S866R

c.2598T>A

12 papers

NM_001322934.2

p.R635*

c.1903C>T

12 papers

NM_001322934.2

p.K855fs

c.2563_2564fs

12 papers

NM_001322934.2

p.S866R

c.2596A>C

12 papers

NM_001322934.2

p.S866R

c.2598T>G

12 papers

NM_001322934.2

p.Q871*

c.2611C>T

11 papers

NM_001322934.2

p.K855delFs

c.2564delA

11 papers

NM_001322934.2

p.K855*

c.2563A>T

11 papers

NM_001322934.2

p.A867fs

c.2599_2600fs