Varaico: Literature-Extracted Genetic Variants

NFKB2

572 papers

RefSeq Summary

This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involv...

Pfam Domains

RHD_DNA_bindaa 40–220UCSCRel homology DNA-binding domain

RHD_dimeraa 229–329UCSCRel homology dimerisation domain

Ankaa 487–521UCSCAnkyrin repeat

Ankaa 526–558UCSCAnkyrin repeat

Ankaa 599–631UCSCAnkyrin repeat

Ankaa 633–666UCSCAnkyrin repeat

Gene Aliases

HGNC Name

nuclear factor kappa B subunit 2

HGNC Alias Symbols

LYT-10; p52; p105; NF-kB2; p49/p100

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001322934.2

p.G849D

c.2546G>A

Surrounding Variants

1 paper

NM_001322934.2

p.P850S

c.2548C>T

2 papers

NM_001322934.2

p.P850fs

c.2548_2549fs

2 papers

NM_001322934.2

p.R848insFs

c.2543_2544insG

3 papers

NM_001322934.2

p.R848fs

c.2542_2543fs

1 paper

NM_001322934.2

p.E851K

c.2551G>A

3 papers

NM_001322934.2

p.E851_T852insFs

c.2553_2554ins7

4 papers

NM_001322934.2

p.L847insFs

c.2540dupT

7 papers

NM_001322934.2

p.T852_K855delFs

c.2556_2563del8

2 papers

NM_001322934.2

p.R853_L856delFs

c.2557_2566del10

1 paper

NM_001322934.2

p.R853R

c.2557C>A

1 paper

NM_001322934.2

p.R853fs

c.2557_2558fs

37 papers

NM_001322934.2

p.R853*

c.2557C>T