Varaico: Literature-Extracted Genetic Variants

NFKB2

572 papers

RefSeq Summary

This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involv...

Pfam Domains

RHD_DNA_bindaa 40–220UCSCRel homology DNA-binding domain

RHD_dimeraa 229–329UCSCRel homology dimerisation domain

Ankaa 487–521UCSCAnkyrin repeat

Ankaa 526–558UCSCAnkyrin repeat

Ankaa 599–631UCSCAnkyrin repeat

Ankaa 633–666UCSCAnkyrin repeat

Gene Aliases

HGNC Name

nuclear factor kappa B subunit 2

HGNC Alias Symbols

LYT-10; p52; p105; NF-kB2; p49/p100

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

37 papers

NM_001322934.2

p.R853*

c.2557C>T

Surrounding Variants

1 paper

NM_001322934.2

p.R853R

c.2557C>A

1 paper

NM_001322934.2

p.R853fs

c.2557_2558fs

9 papers

NM_001322934.2

p.R853fs

c.2557_2558fs

7 papers

NM_001322934.2

p.T852_K855delFs

c.2556_2563del8

2 papers

NM_001322934.2

p.R853_L856delFs

c.2557_2566del10

1 paper

NM_001322934.2

p.D854fs

c.2560_2561fs

2 papers

NM_001322934.2

p.D854delFs

c.2561_2562delAC

2 papers

NM_001322934.2

p.D854fs

c.2560_2561fs

3 papers

NM_001322934.2

p.E851_T852insFs

c.2553_2554ins7

11 papers

NM_001322934.2

p.K855delFs

c.2564delA

1 paper

NM_001322934.2

p.K855fs

c.2563_2564fs

11 papers

NM_001322934.2

p.K855*

c.2563A>T