Varaico: Literature-Extracted Genetic Variants

NLRC4

299 papers

RefSeq Summary

This gene encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage...

Pfam Domains

CARDaa 1–87UCSCCaspase recruitment domain

NACHTaa 163–316UCSCNACHT domain

WHD_Nlrc4aa 385–440UCSCNlrc4-like, winged helix domain

NLRC4_HDaa 465–579UCSCNLRC4 helical domain

Gene Aliases

HGNC Name

NLR family CARD domain containing 4

HGNC Previous Symbol

CARD12

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001199138.2

p.W624R

c.1870T>C

Surrounding Variants

1 paper

NM_001199138.2

p.W624R

c.1870T>A

1 paper

NM_001199138.2

p.E625K

c.1873G>A

1 paper

NM_001199138.2

p.G633R

c.1897G>C

1 paper

NM_001199138.2

p.G633R

c.1897G>A

1 paper

NM_001199138.2

p.K613N

c.1839A>T

1 paper

NM_001199138.2

p.K613N

c.1839A>C

1 paper

NM_001199138.2

p.M636K

c.1907T>A

1 paper

NM_001199138.2

p.F611L

c.1833C>G

1 paper

NM_001199138.2

p.F611L

c.1833C>A

1 paper

NM_001199138.2

p.F611L

c.1831T>C

1 paper

NM_001199138.2

p.A608A

c.1824C>T

1 paper

NM_001199138.2

p.C605S

c.1814G>C