Varaico: Literature-Extracted Genetic Variants

NLRC5

141 papers

RefSeq Summary

This gene encodes a member of the caspase recruitment domain-containing NLR family. This gene plays a role in cytokine response and antiviral immunity through its inhibition of NF-kappa-B activation a...

Pfam Domains

Atypical_Cardaa 1–95UCSCAtypical caspase recruitment domain

NACHTaa 222–383UCSCNACHT domain

HTH_NLRC5aa 451–512UCSCNLRC5, helix-turn-helix domain

NLRC4_HD2aa 514–629UCSCNLRC4 helical domain HD2

LRR_6aa 870–891UCSCLeucine Rich repeat

LRR_6aa 1006–1025UCSCLeucine Rich repeat

Gene Aliases

HGNC Name

NLR family CARD domain containing 5

HGNC Alias Symbols

NOD27; CLR16.1; FLJ21709

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001384950.1

p.C77R

c.229T>C

Surrounding Variants

1 paper

NM_001384950.1

p.L80L

c.240G>A

1 paper

NM_001384950.1

p.D85G

c.254A>G

1 paper

NM_001384950.1

p.L86V

c.256C>G

1 paper

NM_001384950.1

p.V63I

c.187G>A

1 paper

NM_001384950.1

p.T93fs

c.277_278fs

1 paper

NM_001384950.1

p.Q52L

c.155A>T

1 paper

NM_001384950.1

p.E51V

c.152A>T

1 paper

NM_001384950.1

p.E46K

c.136G>A

1 paper

NM_001384950.1

p.D42G

c.125A>G

1 paper

NM_001384950.1

p.L36F

c.106C>T

1 paper

NM_001384950.1

p.V18M

c.52G>A

1 paper

NM_001384950.1

p.M1V

c.1A>G