Varaico: Literature-Extracted Genetic Variants

NLRC5

141 papers

RefSeq Summary

This gene encodes a member of the caspase recruitment domain-containing NLR family. This gene plays a role in cytokine response and antiviral immunity through its inhibition of NF-kappa-B activation a...

Pfam Domains

Atypical_Cardaa 1–95UCSCAtypical caspase recruitment domain

NACHTaa 222–383UCSCNACHT domain

HTH_NLRC5aa 451–512UCSCNLRC5, helix-turn-helix domain

NLRC4_HD2aa 514–629UCSCNLRC4 helical domain HD2

LRR_6aa 870–891UCSCLeucine Rich repeat

LRR_6aa 1006–1025UCSCLeucine Rich repeat

Gene Aliases

HGNC Name

NLR family CARD domain containing 5

HGNC Alias Symbols

NOD27; CLR16.1; FLJ21709

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_001384950.1

p.A155T

c.463G>A

Surrounding Variants

1 paper

NM_001384950.1

p.Q156*

c.466C>T

1 paper

NM_001384950.1

p.T153T

c.459C>T

1 paper

NM_001384950.1

p.R152W

c.454C>T

1 paper

NM_001384950.1

p.L150R

c.449T>G

1 paper

NM_001384950.1

p.P191Q

c.572C>A

5 papers

NM_001384950.1

p.P191L

c.572C>T

1 paper

NM_001384950.1

p.K200R

c.599A>G

1 paper

NM_001384950.1

p.D203V

c.608A>T

1 paper

NM_001384950.1

p.S208N

c.623G>A

2 papers

NM_001384950.1

p.S210L

c.629C>T

1 paper

NM_001384950.1

p.D211N

c.631G>A

1 paper

NM_001384950.1

p.D211V

c.632A>T