Varaico: Literature-Extracted Genetic Variants

NLRC5

141 papers

RefSeq Summary

This gene encodes a member of the caspase recruitment domain-containing NLR family. This gene plays a role in cytokine response and antiviral immunity through its inhibition of NF-kappa-B activation a...

Pfam Domains

Atypical_Cardaa 1–95UCSCAtypical caspase recruitment domain

NACHTaa 222–383UCSCNACHT domain

HTH_NLRC5aa 451–512UCSCNLRC5, helix-turn-helix domain

NLRC4_HD2aa 514–629UCSCNLRC4 helical domain HD2

LRR_6aa 870–891UCSCLeucine Rich repeat

LRR_6aa 1006–1025UCSCLeucine Rich repeat

Gene Aliases

HGNC Name

NLR family CARD domain containing 5

HGNC Alias Symbols

NOD27; CLR16.1; FLJ21709

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001384950.1

p.E275K

c.823G>A

Surrounding Variants

1 paper

NM_001384950.1

p.L280M

c.838C>A

1 paper

NM_001384950.1

p.Y281*

c.843C>A

1 paper

NM_001384950.1

p.Y281*

c.843C>G

1 paper

NM_001384950.1

p.P284T

c.850C>A

1 paper

NM_001384950.1

p.L264P

c.791T>C

2 papers

NM_001384950.1

p.R262C

c.784C>T

1 paper

NM_001384950.1

p.H288H

c.864C>T

1 paper

NM_001384950.1

p.D289N

c.865G>A

1 paper

NM_001384950.1

p.E260K

c.778G>A

1 paper

NM_001384950.1

p.F292delFs

c.874delT

1 paper

NM_001384950.1

p.A255_L256ins1

c.765_766insAGG

1 paper

NM_001384950.1

p.A299T

c.895G>A