Varaico: Literature-Extracted Genetic Variants

NONO

205 papers

RefSeq Summary

This gene encodes an RNA-binding protein which plays various roles in the nucleus, including transcriptional regulation and RNA splicing. A rearrangement between this gene and the transcription factor...

Pfam Domains

RRM_1aa 76–140UCSCRNA recognition motif

RRM_1aa 150–217UCSCRNA recognition motif

NOPSaa 221–272UCSCNOPS (NUC059) domain

Gene Aliases

HGNC Name

non-POU domain containing octamer binding

HGNC Alias Symbols

NRB54; NMT55; P54NRB; P54; PPP1R114

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_007363.5

p.G449R

c.1345G>A

Surrounding Variants

1 paper

NM_007363.5

p.G449R

c.1345G>C

1 paper

NM_007363.5

p.P451S

c.1351C>T

1 paper

NM_007363.5

p.P451H

c.1352C>A

1 paper

NM_007363.5

p.A446V

c.1337C>T

1 paper

NM_007363.5

p.R456C

c.1366C>T

1 paper

NM_007363.5

p.M441fs

c.1321_1322fs

1 paper

NM_007363.5

p.M441_E442delFs

c.1322_1325del4

1 paper

NM_007363.5

p.T440A

c.1318A>G

8 papers

NM_007363.5

p.P459A

c.1375C>G

1 paper

NM_007363.5

p.Q437E

c.1309C>G

13 papers

NM_007363.5

p.P465insFs

c.1394dupC

1 paper

NM_007363.5

p.N466fs

c.1396_1397fs