Varaico: Literature-Extracted Genetic Variants

NOS2

843 papers

RefSeq Summary

Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxi...

Pfam Domains

NO_synthaseaa 135–497UCSCNitric oxide synthase, oxygenase domain

Flavodoxin_1aa 541–672UCSCFlavodoxin

FAD_binding_1aa 725–947UCSCFAD binding domain

NAD_binding_1aa 979–1093UCSCOxidoreductase NAD-binding domain

Gene Aliases

HGNC Name

nitric oxide synthase 2

HGNC Previous Symbol

NOS2A

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000625.4

p.F634Y

c.1901T>A

Surrounding Variants

1 paper

NM_000625.4

p.R633Q

c.1898G>A

1 paper

NM_000625.4

p.A636T

c.1906G>A

2 papers

NM_000625.4

p.Y631*

c.1893C>G

2 papers

NM_000625.4

p.Y631*

c.1893C>A

1 paper

NM_000625.4

p.A638T

c.1912G>A

1 paper

NM_000625.4

p.S646F

c.1937C>T

2 papers

NM_000625.4

p.R620W

c.1858A>T

1 paper

NM_000625.4

p.Q652*

c.1954C>T

1 paper

NM_000625.4

p.E658Q

c.1972G>C

1 paper

NM_000625.4

p.E658K

c.1972G>A

1 paper

NM_000625.4

p.E658A

c.1973A>C

1 paper

NM_000625.4

p.E658D

c.1974A>T