Varaico: Literature-Extracted Genetic Variants

NOS2

843 papers

RefSeq Summary

Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxi...

Pfam Domains

NO_synthaseaa 135–497UCSCNitric oxide synthase, oxygenase domain

Flavodoxin_1aa 541–672UCSCFlavodoxin

FAD_binding_1aa 725–947UCSCFAD binding domain

NAD_binding_1aa 979–1093UCSCOxidoreductase NAD-binding domain

Gene Aliases

HGNC Name

nitric oxide synthase 2

HGNC Previous Symbol

NOS2A

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

20 papers

NM_000625.4

p.I391I

c.1173C>T

Surrounding Variants

2 papers

NM_000625.4

p.I391fs

c.1171_1172fs

1 paper

NM_000625.4

p.Y389S

c.1166A>C

1 paper

NM_000625.4

p.V386insFs

c.1156_1157insT

3 papers

NM_000625.4

p.D385D

c.1155C>T

1 paper

NM_000625.4

p.F383V

c.1147T>G

1 paper

NM_000625.4

p.R381Q

c.1142G>A

1 paper

NM_000625.4

p.R381W

c.1141C>T

1 paper

NM_000625.4

p.G379R

c.1135G>C

1 paper

NM_000625.4

p.G379R

c.1135G>A

1 paper

NM_000625.4

p.M374I

c.1122G>T

1 paper

NM_000625.4

p.M374I

c.1122G>C

1 paper

NM_000625.4

p.M374I

c.1122G>A