Varaico: Literature-Extracted Genetic Variants

NOS2

843 papers

RefSeq Summary

Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxi...

Pfam Domains

NO_synthaseaa 135–497UCSCNitric oxide synthase, oxygenase domain

Flavodoxin_1aa 541–672UCSCFlavodoxin

FAD_binding_1aa 725–947UCSCFAD binding domain

NAD_binding_1aa 979–1093UCSCOxidoreductase NAD-binding domain

Gene Aliases

HGNC Name

nitric oxide synthase 2

HGNC Previous Symbol

NOS2A

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000625.4

p.V352V

c.1056G>T

Surrounding Variants

1 paper

NM_000625.4

p.L356V

c.1066C>G

1 paper

NM_000625.4

p.W346R

c.1036T>A

1 paper

NM_000625.4

p.G361S

c.1081G>A

1 paper

NM_000625.4

p.G361D

c.1082G>A

11 papers

NM_000625.4

p.L342L

c.1026G>T

1 paper

NM_000625.4

p.E363K

c.1087G>A

1 paper

NM_000625.4

p.R340L

c.1019G>T

1 paper

NM_000625.4

p.C367*

c.1101C>A

1 paper

NM_000625.4

p.M374R

c.1121T>G

1 paper

NM_000625.4

p.M374I

c.1122G>T

1 paper

NM_000625.4

p.M374I

c.1122G>C

1 paper

NM_000625.4

p.M374I

c.1122G>A