Varaico: Literature-Extracted Genetic Variants

NOS2

843 papers

RefSeq Summary

Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxi...

Pfam Domains

NO_synthaseaa 135–497UCSCNitric oxide synthase, oxygenase domain

Flavodoxin_1aa 541–672UCSCFlavodoxin

FAD_binding_1aa 725–947UCSCFAD binding domain

NAD_binding_1aa 979–1093UCSCOxidoreductase NAD-binding domain

Gene Aliases

HGNC Name

nitric oxide synthase 2

HGNC Previous Symbol

NOS2A

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000625.4

p.T245N

c.734C>A

Surrounding Variants

1 paper

NM_000625.4

p.A243S

c.727G>T

1 paper

NM_000625.4

p.R241_S242del1

c.723_725delGAC

1 paper

NM_000625.4

p.R250W

c.748C>T

1 paper

NM_000625.4

p.R250P

c.749G>C

1 paper

NM_000625.4

p.R250Q

c.749G>A

74 papers

NM_000625.4

p.A262A

c.786T>C

1 paper

NM_000625.4

p.Y267C

c.800A>G

1 paper

NM_000625.4

p.M272L

c.814A>T

1 paper

NM_000625.4

p.M272L

c.814A>C

1 paper

NM_000625.4

p.P273T

c.817C>A

1 paper

NM_000625.4

p.G275D

c.824G>A

1 paper

NM_000625.4

p.R278K

c.833G>A