Varaico: Literature-Extracted Genetic Variants

NOS2

843 papers

RefSeq Summary

Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxi...

Pfam Domains

NO_synthaseaa 135–497UCSCNitric oxide synthase, oxygenase domain

Flavodoxin_1aa 541–672UCSCFlavodoxin

FAD_binding_1aa 725–947UCSCFAD binding domain

NAD_binding_1aa 979–1093UCSCOxidoreductase NAD-binding domain

Gene Aliases

HGNC Name

nitric oxide synthase 2

HGNC Previous Symbol

NOS2A

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000625.4

p.A220T

c.658G>A

Surrounding Variants

7 papers

NM_000625.4

p.R221W

c.661C>T

1 paper

NM_000625.4

p.R221Q

c.662G>A

1 paper

NM_000625.4

p.E222K

c.664G>A

1 paper

NM_000625.4

p.E222G

c.665A>G

1 paper

NM_000625.4

p.S216G

c.646A>G

1 paper

NM_000625.4

p.R215R

c.645C>T

1 paper

NM_000625.4

p.A214A

c.642C>T

1 paper

NM_000625.4

p.D213V

c.638A>T

1 paper

NM_000625.4

p.I227M

c.681C>G

1 paper

NM_000625.4

p.V211A

c.632T>C

2 papers

NM_000625.4

p.H230H

c.690C>T

1 paper

NM_000625.4

p.G238A

c.713G>C