Varaico: Literature-Extracted Genetic Variants

NOS2

843 papers

RefSeq Summary

Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxi...

Pfam Domains

NO_synthaseaa 135–497UCSCNitric oxide synthase, oxygenase domain

Flavodoxin_1aa 541–672UCSCFlavodoxin

FAD_binding_1aa 725–947UCSCFAD binding domain

NAD_binding_1aa 979–1093UCSCOxidoreductase NAD-binding domain

Gene Aliases

HGNC Name

nitric oxide synthase 2

HGNC Previous Symbol

NOS2A

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

6 papers

NM_000625.4

p.S50S

c.150C>T

Surrounding Variants

1 paper

NM_000625.4

p.Q45Q

c.135G>A

1 paper

NM_000625.4

p.Q45R

c.134A>G

2 papers

NM_000625.4

p.Q58H

c.174G>C

1 paper

NM_000625.4

p.T40S

c.118A>T

1 paper

NM_000625.4

p.K65*

c.193A>T

1 paper

NM_000625.4

p.S37Splc

c.111-134G>A

1 paper

NM_000625.4

p.S67Y

c.200C>A

1 paper

NM_000625.4

p.P68S

c.202C>T

1 paper

NM_000625.4

p.D75V

c.224A>T

1 paper

NM_000625.4

p.A76V

c.227C>T

11 papers

NM_000625.4

p.T77T

c.231C>T

1 paper

NM_000625.4

p.S80T

c.238T>A