neuropeptide S receptor 1

GPR154

PGR14

GPRA

G protein-coupled receptor 154

Neuropeptide S receptor

G-protein coupled receptor 154

G-protein coupled receptor PGR14

G-protein coupled receptor for asthma susceptibility

7 transmembrane receptor (rhodopsin family)

This gene encodes a member of the vasopressin/oxytocin subfamily of G protein-coupled receptors. The encoded membrane protein acts as a receptor for neuropeptide S and affects a variety of cellular processes through its signaling. Increased expression of this gene in ciliated cells of the respiratory epithelium and in bronchial smooth muscle cells is associated with asthma. Polymorphisms in this gene have also been associated with asthma susceptibility, panic disorders, inflammatory bowel disease, and rheumatoid arthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014].

Varaico: Literature-Extracted Genetic Variants

NPSR1

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Previous Symbol