Varaico: Literature-Extracted Genetic Variants

NR1I3

256 papers

RefSeq Summary

This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid...

Pfam Domains

zf-C4aa 9–78UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 157–338UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 1 group I member 3

HGNC Alias Symbols

MB67; CAR1; CAR

Papers

RefSeq ID

Protein change

DNA change

1–12 of 170 variants

23 papers

NM_005122.5

p.P180P

c.540C>T

5 papers

NM_005122.5

p.C28R

c.82T>C

5 papers

NM_005122.5

p.T46A

c.136A>G

4 papers

NM_005122.5

p.H22Y

c.64C>T

4 papers

NM_005122.5

p.H246R

c.737A>G

3 papers

NM_005122.5

p.V12M

c.34G>A

3 papers

NM_005122.5

p.V13E

c.38T>A

3 papers

NM_005122.5

p.T38A

c.112A>G

3 papers

NM_005122.5

p.Q131R

c.392A>G

3 papers

NM_005122.5

p.L141M

c.421C>A

3 papers

NM_005122.5

p.N323S

c.968A>G

2 papers

NM_005122.5

p.A2T

c.4G>A