Varaico: Literature-Extracted Genetic Variants

NR1I3

256 papers

RefSeq Summary

This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid...

Pfam Domains

zf-C4aa 9–78UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 157–338UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 1 group I member 3

HGNC Alias Symbols

MB67; CAR1; CAR

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005122.5

p.S269Y

c.806C>A

Surrounding Variants

1 paper

NM_005122.5

p.S269F

c.806C>T

1 paper

NM_005122.5

p.F268L

c.802T>C

1 paper

NM_005122.5

p.A266A

c.798C>T

1 paper

NM_005122.5

p.V260M

c.778G>A

1 paper

NM_005122.5

p.Y259H

c.775T>C

1 paper

NM_005122.5

p.E256A

c.767A>C

1 paper

NM_005122.5

p.E256Q

c.766G>C

2 papers

NM_005122.5

p.L254F

c.760C>T

1 paper

NM_005122.5

p.L254V

c.760C>G

1 paper

NM_001077473.3

p.R225*

c.673C>T

1 paper

NM_005122.5

p.H246H

c.738T>C

4 papers

NM_005122.5

p.H246R

c.737A>G