Varaico: Literature-Extracted Genetic Variants

NR1I3

256 papers

RefSeq Summary

This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid...

Pfam Domains

zf-C4aa 9–78UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 157–338UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 1 group I member 3

HGNC Alias Symbols

MB67; CAR1; CAR

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_005122.5

p.H246R

c.737A>G

Surrounding Variants

1 paper

NM_005122.5

p.H246H

c.738T>C

1 paper

NM_005122.5

p.H244H

c.732C>T

1 paper

NM_005122.5

p.H244D

c.730C>G

1 paper

NM_005122.5

p.F243L

c.729T>G

1 paper

NM_005122.5

p.F243L

c.729T>A

1 paper

NM_001077482.3

p.F247S

c.740T>C

1 paper

NM_005122.5

p.F243L

c.727T>C

1 paper

NM_001077473.3

p.R225*

c.673C>T

1 paper

NM_005122.5

p.L242I

c.724C>A

1 paper

NM_005122.5

p.E240G

c.719A>G

2 papers

NM_005122.5

p.L254F

c.760C>T

1 paper

NM_005122.5

p.L254V

c.760C>G