Varaico: Literature-Extracted Genetic Variants

NR1I3

256 papers

RefSeq Summary

This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid...

Pfam Domains

zf-C4aa 9–78UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 157–338UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 1 group I member 3

HGNC Alias Symbols

MB67; CAR1; CAR

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005122.5

p.I164S

c.491T>G

Surrounding Variants

1 paper

NM_005122.5

p.D163D

c.489C>T

1 paper

NM_005122.5

p.N165D

c.493A>G

1 paper

NM_005122.5

p.D163G

c.488A>G

1 paper

NM_005122.5

p.A162E

c.485C>A

1 paper

NM_005122.5

p.F161Y

c.482T>A

1 paper

NM_005122.5

p.T159delFs

c.475delT

1 paper

NM_005122.5

p.L155M

c.463C>A

1 paper

NM_005122.5

p.V154M

c.460G>A

1 paper

NM_005122.5

p.P153L

c.458C>T

1 paper

NM_005122.5

p.P149S

c.445C>T

1 paper

NM_005122.5

p.P149T

c.445C>A

1 paper

NM_005122.5

p.L148W

c.443T>G