Varaico: Literature-Extracted Genetic Variants

NR1I3

256 papers

RefSeq Summary

This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid...

Pfam Domains

zf-C4aa 9–78UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 157–338UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 1 group I member 3

HGNC Alias Symbols

MB67; CAR1; CAR

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005122.5

p.L141L

c.423G>A

Surrounding Variants

1 paper

NM_005122.5

p.F142L

c.424T>C

3 papers

NM_005122.5

p.L141M

c.421C>A

1 paper

NM_005122.5

p.H144Y

c.430C>T

1 paper

NM_005122.5

p.A139V

c.416C>T

1 paper

NM_005122.5

p.A139T

c.415G>A

1 paper

NM_005122.5

p.P137A

c.409C>G

1 paper

NM_005122.5

p.P147L

c.440C>T

1 paper

NM_005122.5

p.L148W

c.443T>G

1 paper

NM_005122.5

p.P149S

c.445C>T

1 paper

NM_005122.5

p.P149T

c.445C>A

1 paper

NM_005122.5

p.P153L

c.458C>T

1 paper

NM_005122.5

p.V154M

c.460G>A