Varaico: Literature-Extracted Genetic Variants

NR1I3

256 papers

RefSeq Summary

This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid...

Pfam Domains

zf-C4aa 9–78UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 157–338UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 1 group I member 3

HGNC Alias Symbols

MB67; CAR1; CAR

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_005122.5

p.Q131R

c.392A>G

Surrounding Variants

1 paper

NM_005122.5

p.F129L

c.387T>G

1 paper

NM_005122.5

p.F129L

c.387T>A

1 paper

NM_005122.5

p.V133M

c.397G>A

2 papers

NM_005122.5

p.V133G

c.398T>G

1 paper

NM_005122.5

p.F129L

c.385T>C

1 paper

NM_005122.5

p.Q134fs

c.400_401fs

1 paper

NM_005122.5

p.M125I

c.375G>A

1 paper

NM_005122.5

p.R136_P137Splc

c.408+5G>T

1 paper

NM_005122.5

p.R123C

c.367C>T

1 paper

NM_005122.5

p.T122I

c.365C>T

1 paper

NM_005122.5

p.A120A

c.360C>G

1 paper

NM_005122.5

p.G119G

c.357G>A