Varaico: Literature-Extracted Genetic Variants

NR1I3

256 papers

RefSeq Summary

This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid...

Pfam Domains

zf-C4aa 9–78UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 157–338UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 1 group I member 3

HGNC Alias Symbols

MB67; CAR1; CAR

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005122.5

p.E109E

c.327G>A

Surrounding Variants

1 paper

NM_005122.5

p.E111K

c.331G>A

1 paper

NM_005122.5

p.E112E

c.336G>A

1 paper

NM_005122.5

p.Q110_E112del3

c.328_335del9

1 paper

NM_005122.5

p.V104delFs

c.311delA

1 paper

NM_005122.5

p.R115R

c.345G>A

1 paper

NM_005122.5

p.T116K

c.347C>A

1 paper

NM_005122.5

p.G119G

c.357G>A

1 paper

NM_005122.5

p.A120A

c.360C>G

1 paper

NM_005122.5

p.R98W

c.292C>T

2 papers

NM_005122.5

p.R97W

c.289C>T

1 paper

NM_005122.5

p.T122I

c.365C>T

1 paper

NM_005122.5

p.Q96delFs

c.288delC