Varaico: Literature-Extracted Genetic Variants

NR1I3

256 papers

RefSeq Summary

This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid...

Pfam Domains

zf-C4aa 9–78UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 157–338UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 1 group I member 3

HGNC Alias Symbols

MB67; CAR1; CAR

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_005122.5

p.R97W

c.289C>T

Surrounding Variants

1 paper

NM_005122.5

p.Q96delFs

c.288delC

1 paper

NM_005122.5

p.Q96fs

c.286_287fs

1 paper

NM_005122.5

p.R98W

c.292C>T

1 paper

NM_005122.5

p.A95T

c.283G>A

1 paper

NM_005122.5

p.Q94Q

c.282G>A

1 paper

NM_005122.5

p.K93Q

c.277A>C

1 paper

NM_005122.5

p.R91*

c.271C>T

1 paper

NM_005122.5

p.R91R

c.271C>A

1 paper

NM_005122.5

p.V104delFs

c.311delA

1 paper

NM_005122.5

p.L89L

c.265T>C

1 paper

NM_005122.5

p.E109E

c.327G>A

1 paper

NM_005122.5

p.A84S

c.250G>T