Varaico: Literature-Extracted Genetic Variants

NR1I3

256 papers

RefSeq Summary

This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid...

Pfam Domains

zf-C4aa 9–78UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 157–338UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 1 group I member 3

HGNC Alias Symbols

MB67; CAR1; CAR

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_005122.5

p.H22Y

c.64C>T

Surrounding Variants

1 paper

NM_005122.5

p.Y21F

c.62A>T

1 paper

NM_005122.5

p.F23V

c.67T>G

1 paper

NM_005122.5

p.F23C

c.68T>G

1 paper

NM_005122.5

p.G20D

c.59G>A

1 paper

NM_005122.5

p.F23_N24del2

c.67_71del6

2 papers

NM_005122.5

p.A25V

c.74C>T

1 paper

NM_005122.5

p.A18S

c.52G>T

1 paper

NM_005122.5

p.L26L

c.78G>A

1 paper

NM_005122.5

p.Q17R

c.50A>G

1 paper

NM_005122.5

p.Q17E

c.49C>G

1 paper

NM_005122.5

p.L26_T27delFs

c.76_80del5

5 papers

NM_005122.5

p.C28R

c.82T>C