Varaico: Literature-Extracted Genetic Variants

NR1I3

256 papers

RefSeq Summary

This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid...

Pfam Domains

zf-C4aa 9–78UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 157–338UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 1 group I member 3

HGNC Alias Symbols

MB67; CAR1; CAR

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_005122.5

p.A2A

c.6C>T

Surrounding Variants

1 paper

NM_005122.5

p.A2V

c.5C>T

2 papers

NM_005122.5

p.A2T

c.4G>A

1 paper

NM_005122.5

p.M1K

c.2T>A

1 paper

NM_005122.5

p.D6E

c.18T>G

1 paper

NM_005122.5

p.D6E

c.18T>A

1 paper

NM_005122.5

p.E7K

c.19G>A

1 paper

NM_005122.5

p.L8delFs

c.23_24delCA

1 paper

NM_005122.5

p.N10H

c.28A>C

3 papers

NM_005122.5

p.V12M

c.34G>A

3 papers

NM_005122.5

p.V13E

c.38T>A

1 paper

NM_005122.5

p.V13_C14insFs

c.39_40insTA

1 paper

NM_005122.5

p.V13delFs

c.37_38delAC