Varaico: Literature-Extracted Genetic Variants

NR3C1

1,293 papers

RefSeq Summary

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activ...

Pfam Domains

GCRaa 26–401UCSCGlucocorticoid receptor

zf-C4aa 419–488UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 549–741UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 3 group C member 1

HGNC Previous Symbol

GRL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000176.3

p.L773fs

c.2317_2318fs

Surrounding Variants

3 papers

NM_000176.3

p.L773delFs

c.2317_2318delAG

23 papers

NM_000176.3

p.L773P

c.2318T>C

1 paper

NM_000176.3

p.F774L

c.2320T>C

2 papers

NM_000176.3

p.F774fs

c.2320_2321fs

3 papers

NM_000176.3

p.F774S

c.2321T>C

4 papers

NM_000176.3

p.L773delFs

c.2318_2319delCA

1 paper

NM_000176.3

p.L773fs

c.2317_2318fs

1 paper

NM_000176.3

p.L773V

c.2317C>G

4 papers

NM_000176.3

p.L772insFs

c.2314_2315insA

1 paper

NM_000176.3

p.K771K

c.2313A>G

1 paper

NM_000176.3

p.Q776R

c.2327A>G

2 papers

NM_000176.3

p.K777N

c.2331G>T