Varaico: Literature-Extracted Genetic Variants

NR3C1

1,293 papers

RefSeq Summary

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activ...

Pfam Domains

GCRaa 26–401UCSCGlucocorticoid receptor

zf-C4aa 419–488UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 549–741UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 3 group C member 1

HGNC Previous Symbol

GRL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_000176.3

p.I747T

c.2240T>C

Surrounding Variants

31 papers

NM_000176.3

p.I747M

c.2241T>G

1 paper

NM_000176.3

p.I747I

c.2241T>C

1 paper

NM_000176.3

p.S746I

c.2237G>T

1 paper

NM_000176.3

p.P750A

c.2248C>G

1 paper

NM_000176.3

p.T744T

c.2232C>G

1 paper

NM_000176.3

p.P750P

c.2250C>T

1 paper

NM_000176.3

p.K743M

c.2228A>T

1 paper

NM_000176.3

p.M752T

c.2255T>C

1 paper

NM_000176.3

p.D742V

c.2225A>T

2 papers

NM_000176.3

p.M752I

c.2256G>T

2 papers

NM_000176.3

p.M752I

c.2256G>C

2 papers

NM_000176.3

p.M752I

c.2256G>A