Varaico: Literature-Extracted Genetic Variants

NR3C1

1,293 papers

RefSeq Summary

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activ...

Pfam Domains

GCRaa 26–401UCSCGlucocorticoid receptor

zf-C4aa 419–488UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 549–741UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 3 group C member 1

HGNC Previous Symbol

GRL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000176.3

p.H726P

c.2177A>C

Surrounding Variants

13 papers

NM_000176.3

p.H726R

c.2177A>G

1 paper

NM_000176.3

p.E727G

c.2180A>G

1 paper

NM_000176.3

p.D723G

c.2168A>G

1 paper

NM_000176.3

p.D723N

c.2167G>A

1 paper

NM_000176.3

p.T719_L721delFs

c.2156_2163del8

1 paper

NM_000176.3

p.K720E

c.2158A>G

1 paper

NM_000176.3

p.L718R

c.2153T>G

1 paper

NM_000176.3

p.Y716C

c.2147A>G

2 papers

NM_000176.3

p.Y716S

c.2147A>C

1 paper

NM_000176.3

p.R714L

c.2141G>T

2 papers

NM_000176.3

p.R714P

c.2141G>C

21 papers

NM_000176.3

p.R714Q

c.2141G>A