Varaico: Literature-Extracted Genetic Variants

NR3C1

1,293 papers

RefSeq Summary

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activ...

Pfam Domains

GCRaa 26–401UCSCGlucocorticoid receptor

zf-C4aa 419–488UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 549–741UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 3 group C member 1

HGNC Previous Symbol

GRL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000176.3

p.K703E

c.2107A>G

Surrounding Variants

1 paper

NM_000176.3

p.K703R

c.2108A>G

2 papers

NM_000176.3

p.V702A

c.2105T>C

2 papers

NM_000176.3

p.E705G

c.2114A>G

1 paper

NM_000176.3

p.A700T

c.2098G>A

1 paper

NM_000176.3

p.K699N

c.2097A>T

1 paper

NM_000176.3

p.K699N

c.2097A>C

1 paper

NM_000176.3

p.S708A

c.2122T>G

1 paper

NM_000176.3

p.S708P

c.2122T>C

1 paper

NM_000176.3

p.G698R

c.2092G>C

1 paper

NM_000176.3

p.G698R

c.2092G>A

1 paper

NM_000176.3

p.S709N

c.2126G>A

1 paper

NM_000176.3

p.E696G

c.2087A>G