Varaico: Literature-Extracted Genetic Variants

NR3C1

1,293 papers

RefSeq Summary

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activ...

Pfam Domains

GCRaa 26–401UCSCGlucocorticoid receptor

zf-C4aa 419–488UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 549–741UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 3 group C member 1

HGNC Previous Symbol

GRL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

45 papers

NM_000176.3

p.G679S

c.2035G>A

Surrounding Variants

1 paper

NM_000176.3

p.D678D

c.2034C>T

1 paper

NM_000176.3

p.L680P

c.2039T>C

2 papers

NM_000176.3

p.V675fs

c.2023_2024fs

2 papers

NM_000176.3

p.V675Splc

c.2024-1G>T

2 papers

NM_000176.3

p.E684A

c.2051A>C

2 papers

NM_000176.3

p.D687E

c.2061T>G

2 papers

NM_000176.3

p.D687E

c.2061T>A

1 paper

NM_000176.3

p.E688K

c.2062G>A

1 paper

NM_000176.3

p.E688A

c.2063A>C

1 paper

NM_000176.3

p.Y693D

c.2077T>G

2 papers

NM_000176.3

p.E696*

c.2086G>T

1 paper

NM_000176.3

p.E696G

c.2087A>G